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Fractional Distillation

 Fractional distillation is a separation process used to separate a mixture of liquids into its individual components based on their different boiling points. This technique is commonly used in industries such as petroleum refining, chemical production, and in laboratories.

Pharmaceutical Engineering

How It Works:

Heating the Mixture: The mixture of liquids is heated in a distillation column. As the temperature rises, the component with the lowest boiling point evaporates first.

Vaporization: The vapor rises through a series of trays or packing materials within the distillation column. These trays increase the surface area for vapor-liquid contact, allowing for more efficient separation.

Condensation: As the vapor rises, the temperature decreases, causing some of the vapor to condense back into liquid form on the trays. The condensed liquid is enriched in the higher boiling point components.

Collection of Fractions: The vapor that reaches the top of the column is rich in the lowest boiling point component. It is then condensed and collected as a separate fraction. The process is repeated for other fractions with progressively higher boiling points.

Repeating the Process: The remaining liquid in the column is subjected to further heating, and the next component (with a higher boiling point) evaporates, rises, and is collected similarly.

Applications:

Petroleum Refining: Used to separate crude oil into various fractions such as gasoline, kerosene, diesel, and lubricating oil.

Alcohol Production: Separating ethanol from water in the production of alcoholic beverages.

Chemical Production: Used to purify chemicals by separating them from impurities or other chemicals in the mixture.

Fractional distillation is particularly useful for separating liquids that have close boiling points, as it allows for a more precise separation than simple distillation.






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