Active absorption vs passive absorption

 

B pharmacy notes for exams


Active Absorption:

  • Definition: Active absorption is the process by which cells absorb substances (such as ions or molecules) against their concentration gradient (from lower to higher concentration).
  • Energy Requirement: Requires energy, usually in the form of ATP, since substances are moved against the natural concentration gradient.
  • Carrier Proteins: Involves specific carrier proteins (also called pumps or transporters) in the cell membrane to transport substances.
  • Types:
    • Primary Active Transport: Direct use of ATP (e.g., sodium-potassium pump).
    • Secondary Active Transport: Indirect use of ATP, where energy is stored in ion gradients (e.g., glucose absorption using sodium ion gradient).
  • Examples:
    • Absorption of minerals like calcium, potassium, and sodium in plants.
    • Nutrient absorption in the human intestine (e.g., glucose, amino acids).

2. Passive Absorption:

  • Definition: Passive absorption is the process by which substances are absorbed along their concentration gradient (from higher to lower concentration) without requiring energy.
  • Energy Requirement: No energy is required as the process relies on natural diffusion.
  • Types:
    • Simple Diffusion: Movement of small molecules (e.g., oxygen, carbon dioxide) directly through the cell membrane.
    • Facilitated Diffusion: Involves channel proteins or carrier proteins, but no energy is used. For larger or charged molecules (e.g., glucose via glucose transporter).
    • Osmosis: A specific type of passive absorption for the movement of water through a semi-permeable membrane.
  • Examples:
    • Water absorption in plant roots via osmosis.
    • Movement of gases (O₂ and CO₂) in human lungs and tissues.
    • Absorption of certain ions and small molecules in plant cells.

3. Key Differences:

AspectActive AbsorptionPassive Absorption
Energy RequirementRequires energy (ATP)No energy required
Direction of MovementAgainst concentration gradient (low to high)Along concentration gradient (high to low)
Carrier ProteinsAlways involves carrier proteinsIt may or may not involve carrier proteins
ExamplesAbsorption of minerals, and nutrients in humansWater, gases, and some ions

4. Importance in Biology:

  • Active absorption ensures cells can acquire essential nutrients even when external concentrations are low.
  • Passive absorption allows for the efficient exchange of gases, water, and nutrients without expending energy.

Both mechanisms are essential for maintaining cellular homeostasis and overall organismal function.

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